Metabolome + Transcriptome / Proteome

Service Description

BGI offers multi-omics services to look across genomics, transcriptomics, epigenomics, proteomics and metabolomics, with the flexibility to customize solutions that meet your specific needs. All projects are supported by an advanced bioinformatics infrastructure.

Mass Spectrometry Service Specification

Metabolome platform: Untargeted/Targeted Metabolomics and Lipidomics services. Quantitative Proteome platform: Untargeted and Targeted Quantitative Proteomics services. Transcriptome platform: Transcriptomics services.

Quality Standard

Summary includes data analysis

Reports provided in PDF format, RAW files available upon request

Turn Around Time

Typical 2 weeks from LC-MS/MS raw data acceptance to data report delivery

Sample Requirements

Sample selection for Transcriptome / Proteome and Metabolome should be as consistent as possible.

Metabolome + Transcriptome / Proteome Correlation Analysis

Correlation analysis of metabolome and transcriptome / proteome can simultaneously explore biological problems from the two levels of “cause” and “effect”, mutually verified, and screen out key genes, proteins, metabolites and metabolic pathways, which enables researchers to in-depth follow-up research and applications to fully understand the regulatory mechanism of biological systems. Correlation analysis of metabolome and transcriptome / proteome has been widely used in research of disease pathogenesis, disease diagnosis and typing, animal and plant growth and development, plant stress resistance regulation and other fields

  • Summary includes data analysis
  • Reports provided in PDF format, RAW files available upon request
  • Typical 2 weeks from LC-MS/MS raw data acceptance to data report delivery
INTEGRATIVE ANALYSIS BIOLOGICAL DUPLICATES WHEN 2 GROUPS BIOLOGICAL DUPLICATES WHEN ≥ 3 GROUPS
Transcriptome / Proteome+ metabolome ≥ 8 ≥ 6
Clinical samples ≥ 30 ≥ 30

 

  • Univariate correlation
  • Unsupervised model correlation
  • Supervised model correlation
  • Biological function correlation

Unique DNBSEQ™ Sequencing Technology

BGI’s RNA Sequencing services are typically executed with proprietary DNBSEQ™ sequencing technology platforms, for great sequencing data at some of the lowest costs in the industry. DNBSEQ™ offers advantages in terms of lower amplification error rates and much lower duplication rates. In addition, studies have shown the lower index hopping rate in DNBSEQ™ platforms.