Quantitative Proteomics

Service Description

BGI Genomics participates in quantitative performance assessment as well as standardization and harmonization of Multi-National DIA proteomics analysis supporting precision medicine studies. We have developed innovative solutions for optimizing the process of accurately quantifying proteins in complex biological matrices and other complex mixtures.

Project Workflow

Sample preparation

HPLC FRACTIONATION

LC-MS/MS DDA Analysis

DDA library generation and updates

LC-MS/MS DIA analysis

Quantitation and bioinformatics

Mass Spectrometry Service Specification

Sample Preparation and Services

The QC analysis of enzymatic hydrolysis is strictly controlled by LC-MS

DDA-Spectral Library generated using HPLC technology and sample fractionation

2h/fraction for non blood; and 2h/fraction for non-human blood; 1h/fraction for human blood

Quality Standard

Summary includes all methods and data analysis

Reports provided in Excel or PDF format, RAW files available upon request

Turn Around Time

Typical 4-5 weeks from sample QC acceptance to data report delivery

Unique DNBSEQ™ Sequencing Technology

BGI’s RNA Sequencing services are typically executed with proprietary DNBSEQ™ sequencing technology platforms, for great sequencing data at some of the lowest costs in the industry. DNBSEQ™ offers advantages in terms of lower amplification error rates and much lower duplication rates. In addition, studies have shown the lower index hopping rate in DNBSEQ™ platforms.